Distinct Mechanisms of Biotic and Chemical Elicitors Enable Additive Elicitation of the Anticancer Phytoalexin Glyceollin I
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چکیده
منابع مشابه
Distinct Mechanisms of Biotic and Chemical Elicitors Enable Additive Elicitation of the Anticancer Phytoalexin Glyceollin I.
Phytoalexins are metabolites biosynthesized in plants in response to pathogen, environmental, and chemical stresses that often have potent bioactivities, rendering them promising for use as therapeutics or scaffolds for pharmaceutical development. Glyceollin I is an isoflavonoid phytoalexin from soybean that exhibits potent anticancer activities and is not economical to synthesize. Here, we tes...
متن کاملDevelopment of a radioimmunoassay for the soybean phytoalexin glyceollin I.
A radioimmunoassay for glyceollin I, the major phytoalexin produced by soybean (Glycine max [L.] Merr.), has been developed. Antibodies were raised in rabbits against a glyceollin I-bovine serum albumin conjugate. The antisera were used to establish a radioimmunoassay for glyceollin I using [(125)I]glyceollin I as the tracer. A logit plot of a standard concentration series yielded a straight li...
متن کاملImprovement of alizarin production by different biotic elicitors in Rubiatinctorum by elicitation-infiltration method
Background & Aim: Rubiatinctorum is one of the most well-known medicinal plants whose alizarin and other anthraquinones which are outstanding color agents with some trace of pharmaceutical properties are isolated from it. The objective of this study was to optimize alizarin production in intact plant of R.tinctorum by induction with biotic elicitors. ...
متن کاملImprovement of alizarin production by different biotic elicitors in Rubiatinctorum by elicitation-infiltration method
Background & Aim: Rubiatinctorum is one of the most well-known medicinal plants whose alizarin and other anthraquinones which are outstanding color agents with some trace of pharmaceutical properties are isolated from it. The objective of this study was to optimize alizarin production in intact plant of R.tinctorum by induction with biotic elicitors. ...
متن کاملGlyceollin I, a novel antiestrogenic phytoalexin isolated from activated soy.
Glyceollins, a group of novel phytoalexins isolated from activated soy, have recently been demonstrated to be novel antiestrogens that bind to the estrogen receptor (ER) and inhibit estrogen-induced tumor progression. Our previous publications have focused specifically on inhibition of tumor formation and growth by the glyceollin mixture, which contains three glyceollin isomers (I, II, and III)...
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ژورنال
عنوان ژورنال: Molecules
سال: 2017
ISSN: 1420-3049
DOI: 10.3390/molecules22081261